The present invention relates to a method and an apparatus for transmitting uplink signals to a plurality of transmission points in a wireless communication system, comprising: receiving information on at least one parameter set group through upper layer signaling, wherein each of the at least one parameter set group includes a plurality of parameter sets; detecting a physical downlink control channel (PDCCH) comprising indication information for indicating specific parameter sets which belong to one of the parameter set groups from among the at least one parameter set group; and transmitting a physical uplink shared channel (PUSCH) by using the specific parameter set, wherein each of the plurality of parameter sets includes information on a power control parameter and information on timing advance (TA) for transmitting the PUSCH signal.