A wireless communication method and Multi-SIM user equipment are provided. The wireless communication method for Multi-SIM dual standby (DSDS) technology is applied on Multi-SIM user equipment (UE) which is capable of carrier aggregation (CA) or dual connectivity (DuCo). The wireless communication method includes the steps of determining whether a packet switch (PS) or circuit switch (CS) paging is received on a second SIM card when a first PS call is ongoing in a first SIM card; and suspending the first PS call which is ongoing on the first SIM card if the packet switch (PS) or circuit switch (CS) paging is received on the second SIM card.