A catalyst deterioration determination system determines deterioration of an exhaust gas purification catalyst on the basis of its oxygen storage capacity. The system includes a downstream oxygen concentration sensor having characteristics by which as rich gas components in exhaust gas increase, the oxygen concentration sensor outputs a measurement value of the oxygen concentration corresponding to a richer air-fuel ratio. The system performs a rich shift mode and a lean shift mode based on the measurement value of the oxygen concentration sensor. The rate of change of the exhaust gas air-fuel ratio in at least the lean shift mode is limited to a predetermined rate of change or lower, and the rate of change of the exhaust gas air-fuel ratio in the rich shift mode is set higher than the rate of change of the exhaust gas air fuel ratio in the lean shift mode.