Invention Grant
- Patent Title: Antiviral vaccines with improved cellular immunogenicity
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Application No.: US14632869Application Date: 2015-02-26
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Publication No.: US09670253B2Publication Date: 2017-06-06
- Inventor: Dan H. Barouch , Bette T. Korber , William M. Fischer
- Applicant: Beth Israel Deaconess Medical Center, Inc. , Los Alamos National Security, LLC
- Applicant Address: US MA Boston US NM Los Alamos
- Assignee: Beth Israel Deaconess Medical Center, Inc.,Los Alamos National Security, LLC
- Current Assignee: Beth Israel Deaconess Medical Center, Inc.,Los Alamos National Security, LLC
- Current Assignee Address: US MA Boston US NM Los Alamos
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Main IPC: A61K39/21
- IPC: A61K39/21 ; A61K39/12 ; A61K39/00 ; C07K14/005 ; A61K39/235 ; A61K39/275 ; C12N7/00
Abstract:
The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.
Public/Granted literature
- US20160024156A1 ANTIVIRAL VACCINES WITH IMPROVED CELLULAR IMMUNOGENICITY Public/Granted day:2016-01-28
Information query
