Invention Grant
- Patent Title: 1,3-diaminocyclopentane carboxamide derivatives
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Application No.: US14898491Application Date: 2014-05-09
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Publication No.: US09670142B2Publication Date: 2017-06-06
- Inventor: Christos Tsaklakidis , Wolfgang Staehle , Birgitta Leuthner , Paul Czodrowski , Thomas Fuchss
- Applicant: Merck Patent GmbH
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen White Zelano and Branigan, PC
- Agent Csaba Henter; Anthony Zelano
- Priority: EP13003189 20130621
- International Application: PCT/EP2014/001255 WO 20140509
- International Announcement: WO2014/202168 WO 20141224
- Main IPC: C07C233/79
- IPC: C07C233/79 ; C07D413/14 ; C07D309/04 ; C07D215/12 ; C07D317/50 ; C07D319/18 ; C07D231/12 ; C07D231/56 ; C07D233/26 ; C07D401/04 ; C07D235/06 ; C07D235/18 ; C07D235/26 ; C07D403/04 ; C07D413/04 ; C07D413/12 ; C07D417/04 ; C07D249/18 ; C07D471/04 ; C07D487/04 ; C07D263/57 ; C07D498/04 ; C07D209/08 ; C07D209/14 ; C07D277/62 ; C07D277/66 ; C07D209/30 ; C07D209/34 ; C07D209/42 ; C07D213/56 ; C07C255/57 ; C07C235/42 ; A61K31/166 ; A61K31/277 ; A61K31/4164 ; A61K31/4184 ; A61K31/423 ; A61K31/428 ; A61K31/451 ; A61K31/501 ; A61K31/519 ; C07C231/10 ; C07C253/30 ; C07C255/60 ; C07D233/58

Abstract:
Compounds of the formula I in which R1, R4, R6, R, X1, X2, X3, X4, q and W have the meanings indicated in claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Public/Granted literature
- US20160130214A1 1,3-DIAMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES Public/Granted day:2016-05-12
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