- Patent Title: (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and hepatocellular carcinoma
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Application No.: US15289480Application Date: 2016-10-10
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Publication No.: US09670141B2Publication Date: 2017-06-06
- Inventor: Richard B. Silverman , Kenji Takaya , Hoang V. Le , Jose I. Juncosa
- Applicant: NORTHWESTERN UNIVERSITY
- Applicant Address: US IL Evanston
- Assignee: NORTHWESTERN UNIVERSITY
- Current Assignee: NORTHWESTERN UNIVERSITY
- Current Assignee Address: US IL Evanston
- Agency: Carter, DeLuca, Farrell & Schmidt, LLP
- Main IPC: C07C229/48
- IPC: C07C229/48 ; A61K31/205 ; A61K31/196

Abstract:
Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
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