There is provided a vehicle body framework structure, the vehicle body framework structure including (1) a framework main body that is provided with a closed cross-sectional structure which is formed by joining together a first panel, and a second panel having less strength than the first panel, and (2) a cylindrical reinforcing member that is provided inside the framework main body and extends along the framework main body, a portion of the cylindrical reinforcing member that is located on the second panel side being formed thicker overall than a portion of the cylindrical reinforcing member that is located on the first panel side.