A dose setting mechanism for an injection device having a rotatably operated dose setting member, a presetting member being operable to limit the maximum dose settable by the dose setting member, and a first stopping member is operatively connected to the presetting member where the position of the first stopping member indicates the preset maximum dose. The first stopping member is adapted to rotatably engage with a second stopping member when the preset maximum dose has been set, thereby preventing setting of a further dose. The first and/or the second stopping member is/are movable along with the dose setting member, the first and second stopping members thereby being moved into engagement when a dose is set. Thereby a dose can be preset and the preset dose can easily be repeatedly set while ensuring an accurate dosage. The contemplated device can aid persons being visually impaired or having poor dexterity in setting a correct and accurate dose.