A method and system for pre-configuring a UE with timing advance for use in communication with a handover target. When a UE is being served by a handover source, the handover source transmits to a handover target a measurement request that specifies an uplink reference signal that the UE will provide, and the handover target evaluates that uplink reference signal to determine a timing advance for the UE and reports the timing advance in a response to the handover source. As the handover source then directs the UE to hand over to the handover target, the handover source provides the UE with an indication of the timing advance provided by the handover target. The UE may then transition to be served by the handover target and to make use of the indicated timing advance.