A distortion compensation circuit compensates for the distortions generated by the dispersion-slope of an optical component and the frequency chirp of an optical transmitter. The dispersion compensation circuitry can be utilized in the optical transmitter, the optical receiver and/or at some intermediate point in a fiber-optic network. One embodiment of the compensation circuit utilizes a primary electrical signal path that receives at least a portion of the input signal and a delay line; and a secondary signal path in parallel to the primary path that receives at least a portion of the input signal and including: an amplifier with an electrical current gain that is proportional to the dispersion-slope of the optical component, an optional RF attenuator, an optional delay line, a “squarer” circuit, and a “differentiator” circuit. Another embodiment of the disclosure performs simultaneous, and independent, compensation of second-order distortions generated by both the dispersion-slope of a first optical component and the dispersion of a second optical component. Other embodiments of the disclosure perform adaptive predistortion for compensation of distortions generated by the dispersion-slope of a first optical component and the dispersion of a second optical component to maintain optimum compensation even if the dispersion properties of the optical components change with time.