One embodiment sets forth a technique for time-multiplexed communication for transmitting command and address information between a controller and a multi-port memory device over a single connection. Command and address information for each port of the multi-port memory device is time-multiplexed within the controller to produce a single stream of commands and addresses for different memory requests. The single stream of commands and addresses is transmitted by the controller to the multi-port memory device where the single stream is demultiplexed to generate separate streams of commands and addresses for each port of the multi-port memory device.