Provided are a storage chip, an imaging cartridge, a method for changing a serial number and a method of using the storage chip. The storage chip includes a communication unit, a control unit and a storage unit; the storage unit stores information of multiple different serial numbers and mark information or access mark information about whether a currently-selected serial number is legal; the control unit determines whether the serial number information sent to the imaging device is determined as legal according to a preset strategy and autonomously changes the selected serial number information when a preset condition is satisfied according to the determination result, so that the method of changing the serial number of the storage chip is more convenient, user experience is greatly improved and the problem that the storage chips are unusable because of the same serial number can be solved.