Methods and systems are provided for addressing pre-ignition that may be induced in response to actions taken to mitigate a cylinder misfire. An amount of engine load limiting applied may be adjusted to reduce the likelihood pre-ignition while also addressing component over-temperature issues. By limiting an engine load while shutting off fuel in a misfiring cylinder, and while combusting a lean air-fuel mixture in the remaining cylinders, pre-ignition induced by the misfire-mitigating lean combustion conditions can be reduced.