Invention Grant
- Patent Title: Human-derived bacteria that induce proliferation or accumulation of regulatory T cells
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Application No.: US15019068Application Date: 2016-02-09
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Publication No.: US09642881B2Publication Date: 2017-05-09
- Inventor: Kenya Honda , Koji Atarashi , Takeshi Tanoue , Masahira Hattori , Hidetoshi Morita
- Applicant: The University of Tokyo , School Corporation, Azabu Veterinary Medicine Educational Institution
- Applicant Address: JP Tokyo JP Kanagawa
- Assignee: The University of Tokyo,School Corporation, Azabu Veterinary Medicine Educational Institution
- Current Assignee: The University of Tokyo,School Corporation, Azabu Veterinary Medicine Educational Institution
- Current Assignee Address: JP Tokyo JP Kanagawa
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K35/74
- IPC: A61K35/74 ; C12R1/145 ; A61K35/741 ; A61K35/742 ; A61K45/06 ; C12N1/20 ; C12Q1/04 ; C12Q1/68 ; A61K35/00
Abstract:
Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
Public/Granted literature
- US20160193256A1 HUMAN-DERIVED BACTERIA THAT INDUCE PROLIFERATION OR ACCUMULATION OF REGULATORY T CELLS Public/Granted day:2016-07-07
Information query
