Invention Grant
- Patent Title: Pharmaceutical dosage form for oral administration of a bcl 2 family inhibitor
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Application No.: US12796000Application Date: 2010-06-08
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Publication No.: US09642796B2Publication Date: 2017-05-09
- Inventor: Claudia Packhaeuser , Norbert Steiger , Bernd Liepold , Drazen Kostelac , Martin Knobloch
- Applicant: Claudia Packhaeuser , Norbert Steiger , Bernd Liepold , Drazen Kostelac , Martin Knobloch
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: A61K9/48
- IPC: A61K9/48 ; A61K9/00 ; A61K9/14 ; A61K31/635

Abstract:
The invention relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The invention is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders.
Public/Granted literature
- US20100310648A1 PHARMACEUTICAL DOSAGE FORM FOR ORAL ADMINISTRATION OF A BCL 2 FAMILY INHIBITOR Public/Granted day:2010-12-09
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