An information handling system communicates through plural wireless interfaces with plural external wireless devices by automatically selecting associated external wireless devices based upon the proximity of the information handling system to the devices. Positioning of wireless devices is stored in memory to allow a wireless transceiver of the information handling system to power down until within range of a wireless device of interest. For example, an information handling system interfaced with a WLAN through a wireless access point retrieves a wireless device map with wireless devices of one or more work zones located in the WLAN area, each work zone having a set of one or more wireless peripherals in connectivity stations.