Invention Grant
- Patent Title: Antibody Fc mutants with ablated effector functions
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Application No.: US14597690Application Date: 2015-01-15
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Publication No.: US09637549B2Publication Date: 2017-05-02
- Inventor: William Strohl , Omid Vafa
- Applicant: Janssen Biotech, Inc.
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Eric Dichter
- Main IPC: C07K16/32
- IPC: C07K16/32 ; C07K16/00 ; C07K16/28 ; A61K38/00 ; A61K39/00
Abstract:
Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
Public/Granted literature
- US20150118227A1 Antibody Fc Mutants with Ablated Effector Functions Public/Granted day:2015-04-30
Information query
