Invention Grant
- Patent Title: Isoxazoline hydroxamic acid derivatives as LpxC inhibitors
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Application No.: US15304044Application Date: 2015-04-22
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Publication No.: US09637482B2Publication Date: 2017-05-02
- Inventor: Jiping Fu , Xianming Jin , Subramanian Karur , Guillaume Lapointe , Patrick Lee , Zachary Kevin Sweeney
- Applicant: Jiping Fu , Xianming Jin , Subramanian Karur , Guillaume Lapointe , Patrick Lee , Zachary Kevin Sweeney
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Michael G. Smith
- International Application: PCT/US2015/027009 WO 20150422
- International Announcement: WO2015/164458 WO 20151029
- Main IPC: C07D417/10
- IPC: C07D417/10 ; C07D261/04 ; A61K31/421 ; A61K45/06 ; C07D413/04 ; A61K31/4439 ; C07D413/10 ; A61K31/422 ; A61K31/5377
Abstract:
This invention pertains generally to compounds of Formula I and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention pertains to methods and compositions for treating infections caused by Gram-negative bacteria.
Public/Granted literature
- US20170029415A1 ISOXAZOLINE HYDROXAMIC ACID DERIVATIVES AS LpxC INHIBITORS Public/Granted day:2017-02-02
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