Invention Grant
US09587252B2 Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
有权
正交Cas9蛋白用于RNA指导基因调控和编辑
- Patent Title: Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
- Patent Title (中): 正交Cas9蛋白用于RNA指导基因调控和编辑
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Application No.: US14674895Application Date: 2015-03-31
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Publication No.: US09587252B2Publication Date: 2017-03-07
- Inventor: George M. Church , Kevin Esvelt , Prashant Mali
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Banner & Witcoff, Ltd.
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N9/22 ; C12N15/90 ; C12N15/85 ; C07K2/00 ; C12N15/11
Abstract:
Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes.
Public/Granted literature
- US20150259684A1 Orthogonal Cas9 Proteins for RNA-Guided Gene Regulation and Editing Public/Granted day:2015-09-17
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