Invention Grant
- Patent Title: Low-molecular-compound for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the same, and culture method
- Patent Title (中): 用于改善多能干细胞的生产，维持和增殖的低分子化合物，包含其的组合物和培养方法
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Application No.: US14358672Application Date: 2012-11-08
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Publication No.: US09587225B2Publication Date: 2017-03-07
- Inventor: Yee Sook Cho , Kyeong Lee , Jung Woon Lee
- Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
- Applicant Address: KR Daejeon
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Daejeon
- Agency: Lathrop & Gage LLP
- Agent Andrew T. Wilkins, Esq.; Brian C. Trinque, Esq.
- Priority: KR10-2012-0056881 20120529; KR10-2012-0057803 20120530
- International Application: PCT/KR2012/009420 WO 20121108
- International Announcement: WO2013/180350 WO 20131205
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/074 ; C07D209/20 ; C07D209/18 ; C07D209/24 ; C07D405/12
Abstract:
Provided herein are novel indoleacrylic acid-based compounds, and pharmaceutically acceptable salts thereof, useful for the production, maintenance and proliferation of pluripotent stem cells. Also provided are cell culture compositions comprising these compounds, and methods of using these compounds in the production and maintenance of pluripotent stem cells.
Public/Granted literature
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