Invention Grant
- Patent Title: Compositions and methods of use for (pro)renin receptor
- Patent Title (中): （pro）肾素受体的组合物和使用方法
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Application No.: US14449714Application Date: 2014-08-01
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Publication No.: US09586995B2Publication Date: 2017-03-07
- Inventor: Yumei Feng , Tianxin Yang
- Applicant: University of Utah
- Applicant Address: US UT Salt Lake City
- Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee Address: US UT Salt Lake City
- Agency: Ballard Spahr LLP
- Main IPC: C07K7/08
- IPC: C07K7/08 ; A61K38/43 ; A61K38/00
Abstract:
Disclosed are methods of treating kidney disease, infectious or inflammatory diseases, acute kidney injury and hypertension by administering a (pro)renin receptor (PRR) antagonist. In some instances the PRR antagonist is a polypeptide. The PRR antagonist can be a polypeptide having at least 70% identity to the amino acid sequence set forth in SEQ ID NO:2. Also disclosed are methods of decreasing proteinuria and methods of promoting wound healing by administering a PRR antagonist.
Public/Granted literature
- US20150025013A1 Compositions And Methods Of Use For (PRO)Renin Receptor Public/Granted day:2015-01-22
Information query
