Invention Grant
- Patent Title: Soluble mediator
- Patent Title (中): 可溶性介体
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Application No.: US14351501Application Date: 2012-11-15
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Publication No.: US09585969B2Publication Date: 2017-03-07
- Inventor: Esther Bandala Sanchez , James Dromey , Leonard Charles Harrison , Yuxia Zhang
- Applicant: The Walter and Eliza Hall Institute of Medical Research
- Applicant Address: AU Parkville
- Assignee: The Walter and Eliza Hall Institute of Medical Research
- Current Assignee: The Walter and Eliza Hall Institute of Medical Research
- Current Assignee Address: AU Parkville
- Agency: Bozicevic, Field & Francis LLP
- Agent Shweta Chandra
- International Application: PCT/AU2012/001411 WO 20121115
- International Announcement: WO2013/071355 WO 20130523
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K47/48 ; C07K14/705 ; G01N33/68 ; C12N5/0783 ; C07K16/18 ; C12Q1/68 ; G01N33/50 ; A61K48/00
Abstract:
The present disclosure relates to a soluble CD52 glycoprotein and its use in treating diseases regulated by effector T-cells, for example autoimmune diseases such as type 1 diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of CD52, and to diagnostic methods based on the detection of CD52 expression levels in a subject.
Public/Granted literature
- US20140308209A1 Soluble Mediator Public/Granted day:2014-10-16
Information query
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