Invention Grant
- Patent Title: Nitrogen-containing bicyclic aromatic heterocyclic compound
- Patent Title (中): 含氮双环芳族杂环化合物
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Application No.: US15017914Application Date: 2016-02-08
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Publication No.: US09585889B2Publication Date: 2017-03-07
- Inventor: Yutaka Nakajima , Sunao Imada , Yuji Takasuna , Naohiro Aoyama , Takahiro Nigawara , Shohei Shirakami , Fumiyuki Shirai , Junji Sato , Keita Nakanishi , Kaori Kubo
- Applicant: ASTELLAS PHARMA INC.
- Applicant Address: JP Chuo-ku
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Chuo-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2012-094278 20120417; JP2013-051487 20130314
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/52 ; C07D473/00 ; C07D487/04 ; A61K31/5377
Abstract:
On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. It was found that a nitrogen-containing bicyclic heterocyclic compound has an excellent cathepsin S inhibitory effect, thereby completing the invention. The compound of the present invention has an cathepsin S inhibitory effect, and can be used as an agent for preventing and/or treating autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like.
Public/Granted literature
- US20160228442A1 NITROGEN-CONTAINING BICYCLIC AROMATIC HETEROCYCLIC COMPOUND Public/Granted day:2016-08-11
Information query
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