An end effector assembly for use with a surgical instrument. The end effector assembly can comprise an anvil, a fastener cartridge including fastener cavities, fasteners removably positioned in the fastener cavities, a piece of buttress material releasably secured intermediate the anvil and the fastener cartridge, a connector, and an actuator configured to overcome the connector when actuated. The connector can secure the piece of buttress material relative to the anvil or the fastener cartridge at a location that is distal to at least one fastener cavity. The actuator can overcome the connector prior to the removal of the fasteners from the fastener cavities. Further, the actuator can extend past the fasteners in the fastener cavities, and can be actuated proximal to the fastener cavities.