Management of power consumption in large computing clusters is disclosed herein. According to an aspect, a computing device comprising a power manager may be configured to receive, via a communication interface, information associated with the cluster of computing nodes. The power manager of the computing device may also be configured to determine whether a switch is coupled to an inactive computing node of the cluster of computing nodes based on the received information. Further, the power manager of the computing device may be configured to communicate a command to the switch to remove power supplied to a switch port of the switch coupled to the inactive computing node in response to determining that the switch is coupled to an inactive computing node of the cluster of computing nodes.