Invention Grant
- Patent Title: Fibronectin based scaffold proteins having improved stability
- Patent Title (中): 基于纤连蛋白的支架蛋白具有改善的稳定性
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Application No.: US13699458Application Date: 2011-05-26
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Publication No.: US09562089B2Publication Date: 2017-02-07
- Inventor: Ray Camphausen , John O'Loughlin , Bernice Yeung , Yihong Zhang
- Applicant: Ray Camphausen , John O'Loughlin , Bernice Yeung , Yihong Zhang
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- International Application: PCT/US2011/038013 WO 20110526
- International Announcement: WO2011/150133 WO 20111201
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K14/78 ; C07K14/435 ; C07K16/46 ; A61K38/39 ; A61K38/17 ; A61K38/18 ; C07K14/71 ; C07K14/715 ; C07K16/28
Abstract:
The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
Public/Granted literature
- US20130184212A1 FIBRONECTIN BASED SCAFFOLD PROTEINS HAVING IMPROVED STABILITY Public/Granted day:2013-07-18
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