Invention Grant
US09561270B2 Methods of reducing virucidal activity in PCV-2 compositions and PCV-2 compositions with an improved immunogenicity
有权
降低PCV-2组合物和PCV-2组合物中具有改善免疫原性的杀病毒活性的方法
- Patent Title: Methods of reducing virucidal activity in PCV-2 compositions and PCV-2 compositions with an improved immunogenicity
- Patent Title (中): 降低PCV-2组合物和PCV-2组合物中具有改善免疫原性的杀病毒活性的方法
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Application No.: US12874994Application Date: 2010-09-02
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Publication No.: US09561270B2Publication Date: 2017-02-07
- Inventor: Caroline Ann Kohler , Guosong Zhao , Ali Khazraeinazmpour , Bernd Colin Eichenmueller , Marc Allan Eichmeyer , Gregory Haiwick , Merrill Lynn Schaeffer
- Applicant: Caroline Ann Kohler , Guosong Zhao , Ali Khazraeinazmpour , Bernd Colin Eichenmueller , Marc Allan Eichmeyer , Gregory Haiwick , Merrill Lynn Schaeffer
- Applicant Address: US MO St. Joseph
- Assignee: Boehringer Ingelheim Vetmedica, Inc.
- Current Assignee: Boehringer Ingelheim Vetmedica, Inc.
- Current Assignee Address: US MO St. Joseph
- Agent Michael P. Morris; Wendy M. Gombert
- Main IPC: C12N7/02
- IPC: C12N7/02 ; A61K39/12 ; A61K39/00
Abstract:
The present invention provides methods of reducing the virucidal activity of a composition comprising a PCV-2 antigen as well as antigenic preparations and immunogenic compositions comprising a PCV-2 antigen, wherein the virucidal activity has been reduced. In addition, the present invention also relates to a method of increasing the immunogenicity of an immunogenic composition comprising a PCV-2 antigen as well as immunogenic composition with an increased immunogenicity.
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