Invention Grant
- Patent Title: Combined organ and hematopoietic cells for transplantation tolerance of grafts
- Patent Title (中): 组织器官和造血细胞移植耐受移植物
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Application No.: US14438159Application Date: 2014-02-07
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Publication No.: US09561253B2Publication Date: 2017-02-07
- Inventor: Samuel Strober , Robert Lowsky
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- International Application: PCT/US2014/015394 WO 20140207
- International Announcement: WO2014/133729 WO 20140904
- Main IPC: A61K35/28
- IPC: A61K35/28 ; A61K35/26 ; A61K35/22 ; A61K35/14 ; A61K38/19 ; A61K41/00 ; A61K45/06 ; A61K35/12
Abstract:
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is established through development of a persistent mixed chimerism. An individual with persistent mixed chimerism, usually for a period of at least six months, is able to withdraw from the use of immunosuppressive drugs after a period of time sufficient to establish tolerance.
Public/Granted literature
- US20150272993A1 Combined Organ and Hematopoietic Cells For Transplantation Tolerance of Grafts Public/Granted day:2015-10-01
Information query
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