Invention Grant
- Patent Title: Morpholinos, morpholino upregulating, and associated methods
- Patent Title (中): 吗啉代，吗啉上调和相关方法
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Application No.: US14358572Application Date: 2012-11-15
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Publication No.: US09534222B2Publication Date: 2017-01-03
- Inventor: Balamurali K. Ambati , Hironori Uehara
- Applicant: Balamurali K. Ambati , Hironori Uehara
- Applicant Address: US UT Salt Lake City
- Assignee: University of Utah Research Foundation
- Current Assignee: University of Utah Research Foundation
- Current Assignee Address: US UT Salt Lake City
- Agency: Thorpe North & Western, LLP
- International Application: PCT/US2012/065320 WO 20121115
- International Announcement: WO2013/074814 WO 20130523
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113
Abstract:
Various methods and compositions relating to vascular endothelial growth factor receptor 2 (VEGFR2) are provided. In one aspect, a method of increasing expression of the soluble form of VEGFR2 (sVEGFR2) in a subject can include binding an antisense morphoiino to an exon13-intron13 splicing site of VEGFR2 mRNA such that the VEGFR2 niRNA is spliced into a sVEGFR2 isoform.
Public/Granted literature
- US20160040169A1 MORPHOLINOS, MORPHOLINO UPREGULATING, AND ASSOCIATED METHODS Public/Granted day:2016-02-11
Information query
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