Invention Grant
- Patent Title: TIKI inhibitors
- Patent Title (中): TIKI抑制剂
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Application No.: US14391971Application Date: 2013-04-12
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Publication No.: US09534059B2Publication Date: 2017-01-03
- Inventor: Xi He , Xinjun Zhang , Bryan MacDonald
- Applicant: Children's Medical Center Corporation
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporation
- Current Assignee: Children's Medical Center Corporation
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2013/036422 WO 20130412
- International Announcement: WO2013/155447 WO 20131017
- Main IPC: C07K16/40
- IPC: C07K16/40 ; A61K39/395 ; A61K31/713 ; C12N15/113 ; C12N9/64 ; A61K31/7088
Abstract:
Modulators of Wnt activity, e.g., Wnt inhibitors, that act on TIKI proteins and inhibit TIKI-mediated cleavage of Wnt proteins, as well as methods of identifying such modulators and methods of use thereof.
Public/Granted literature
- US20150166671A1 TIKI INHIBITORS Public/Granted day:2015-06-18
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