Invention Grant
- Patent Title: Therapeutic human anti-IL-1R1 monoclonal antibody
- Patent Title (中): 治疗性人类抗IL-1R1单克隆抗体
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Application No.: US14198131Application Date: 2014-03-05
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Publication No.: US09534053B2Publication Date: 2017-01-03
- Inventor: Brian Varnum , Chris Vezina , Alison Witte , Xueming Qian , Francis Hall Martin , Haichun Huang , Gary Elliott
- Applicant: Medarex, L.L.C. , Amgen Inc.
- Applicant Address: US CA Thousand Oaks US NJ Princeton
- Assignee: Amgen Inc.,E.R. Squibb & Sons, L.L.C.
- Current Assignee: Amgen Inc.,E.R. Squibb & Sons, L.L.C.
- Current Assignee Address: US CA Thousand Oaks US NJ Princeton
- Agency: Ropes & Gray LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00
Abstract:
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
Public/Granted literature
- US20140335099A1 THERAPEUTIC HUMAN ANTI-IL-1R1 MONOCLONAL ANTIBODY Public/Granted day:2014-11-13
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