Invention Grant
US09533975B2 Dual-action, unnatural proline-rich peptides as antibiotic agents and methods thereof
有权
作为抗生素的双作用，非天然富含脯氨酸的肽及其方法
- Patent Title: Dual-action, unnatural proline-rich peptides as antibiotic agents and methods thereof
- Patent Title (中): 作为抗生素的双作用，非天然富含脯氨酸的肽及其方法
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Application No.: US14702530Application Date: 2015-05-01
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Publication No.: US09533975B2Publication Date: 2017-01-03
- Inventor: Jean Anne Chmielewski
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Faegre Baker Daniels LLP
- Main IPC: C07K7/06
- IPC: C07K7/06 ; C07D405/14 ; A61K47/48 ; A61K31/7036 ; A61K49/00 ; C07K5/083 ; A61K38/00
Abstract:
The present invention cationic amphiphilic polyproline helices (CAPHs) compounds having increased hydrophobicity and cellular internalization as antimicrobial agents. Antimicrobial compositions and methods of using the same are also provided.
Public/Granted literature
- US20150314009A1 DUAL-ACTION, UNNATURAL PROLINE-RICH PEPTIDES AS ANTIBIOTIC AGENTS AND METHODS THEREOF Public/Granted day:2015-11-05
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