Invention Grant
US09532989B2 Oxadiazolo[3,2-A]pyrimidines and thiadiazolo[3,2-A]pyrimidines
有权
氧杂双环[3,2-A]嘧啶和噻二唑并[3,2-A]嘧啶
![Oxadiazolo[3,2-A]pyrimidines and thiadiazolo[3,2-A]pyrimidines](/docs/US/2017-01-03/US09532989B2/abs.jpg.600x600.jpg)
- Patent Title: Oxadiazolo[3,2-A]pyrimidines and thiadiazolo[3,2-A]pyrimidines
- Patent Title (中): 氧杂双环[3,2-A]嘧啶和噻二唑并[3,2-A]嘧啶
-
Application No.: US14730707Application Date: 2015-06-04
-
Publication No.: US09532989B2Publication Date: 2017-01-03
- Inventor: Barry S. Coller , Craig Thomas , Marta Filizola , Joshua McCoy , Wenwei Huang , Min Shen
- Applicant: The United States of America, as Represented by the Secretary, Department of Health and Human Services , The Rockefeller University , Icahn School of Medicine at Mount Sinai
- Applicant Address: US DC Washington US NY New York US NY New York
- Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES,ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI,THE ROCKEFELLER UNIVERSITY
- Current Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES,ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI,THE ROCKEFELLER UNIVERSITY
- Current Assignee Address: US DC Washington US NY New York US NY New York
- Agency: Cantor Colburn LLP
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D487/04 ; A61K31/497 ; A61K45/06 ; C07D513/04
![Oxadiazolo[3,2-A]pyrimidines and thiadiazolo[3,2-A]pyrimidines](/abs-image/US/2017/01/03/US09532989B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds of Formula P-I where the variables (e.g. R1, Y, A, R1, Ra, Ra′, Rb, Rb′, Rc, Rc′, Rd, Rd′, Re, or Re′) and compositions useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The present invention further relates to methods for the treatment or prophylaxis of thrombotic disorders, including stroke, myocardial infarction, unstable angina, peripheral vascular disease, abrupt closure following angioplasty or stent placement and thrombosis as a result of vascular surgery.
Public/Granted literature
- US20150374697A1 ORGANIC COMPOUNDS Public/Granted day:2015-12-31
Information query
IPC分类:
