Systems described herein enable PCIe device components to be used with multiple PCIe topologies and with host systems of varying configurations. In some cases, a number of varying PHYs and PCIe cores are utilized to increase the number of applications and/or specifications that may be satisfied with a host interface design. Further, some systems described herein may include a number of synchronizers, clock multiplier units, and selectors to create a host interface that can be configured for a number of applications. Despite increasing the flexibility of the usage of systems disclosed herein, costs can be reduced by using the systems of the present disclosure for PCIe based devices.