A computer system includes a removable computer module. The computer module includes a retaining mechanism securing the computer module within a computer system chassis of the computer system. The computer module further includes a retaining mechanism protection device preventing access to the retaining mechanism. To remove the computer module from the computer system chassis, a user must move the retaining mechanism protection device. Upon notification of movement of the retaining mechanism protection device, the CPU takes the appropriate operations to disable the functionality of the computer module and allow safe removal thereof without powering down the computer system.