Invention Grant
US09434944B2 Modulators of miR-323-3p for the prevention or treatment of rheumatoid arthritis
有权
miR-323-3p调节剂用于预防或治疗类风湿性关节炎
- Patent Title: Modulators of miR-323-3p for the prevention or treatment of rheumatoid arthritis
- Patent Title (中): miR-323-3p调节剂用于预防或治疗类风湿性关节炎
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Application No.: US14241456Application Date: 2012-08-31
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Publication No.: US09434944B2Publication Date: 2016-09-06
- Inventor: Steffen Gay , Mary Connolly , Caroline Ospelt
- Applicant: Steffen Gay , Mary Connolly , Caroline Ospelt
- Applicant Address: CH Zurich
- Assignee: UNIVERSITY OF ZURICH
- Current Assignee: UNIVERSITY OF ZURICH
- Current Assignee Address: CH Zurich
- Agency: JMB Davis Ben-David
- Priority: EP11179646 20110831
- International Application: PCT/EP2012/067011 WO 20120831
- International Announcement: WO2013/030362 WO 20130307
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; C07H21/04
Abstract:
A miR-323-3p inhibitor is provided for the prevention or therapy of rheumatoid arthritis, comprising a sequence capable of forming a hybrid to miR-323-3p as an oligonucleotide or a vector from which such oligonucleotide is transcribed, or as a miRNA decoy or sponge.
Public/Granted literature
- US20140193366A1 Modulators of miR-323-3p for the Prevention or Treatment of Rheumatoid Arthritis Public/Granted day:2014-07-10
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