Invention Grant
US09434735B2 Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
有权
4 - ((4-(环戊氧基)-5-(2-甲基苯并[d]恶唑-6-基)-7H-吡咯并[2,3-d]嘧啶-2-基)氨基)-3- 甲氧基 - 正 - 甲基苯甲酰胺,其组合物及其使用方法
- Patent Title: Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
- Patent Title (中): 4 - ((4-(环戊氧基)-5-(2-甲基苯并[d]恶唑-6-基)-7H-吡咯并[2,3-d]嘧啶-2-基)氨基)-3- 甲氧基 - 正 - 甲基苯甲酰胺,其组合物及其使用方法
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Application No.: US14797542Application Date: 2015-07-13
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Publication No.: US09434735B2Publication Date: 2016-09-06
- Inventor: Ming J. Chen , Jale Muslehiddinoglu , Alexander Ruchelman , Terrence Joseph Connolly
- Applicant: Signal Pharmaceuticals, LLC
- Applicant Address: US CA San Diego
- Assignee: Signal Pharmaceuticals, LLC
- Current Assignee: Signal Pharmaceuticals, LLC
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Main IPC: C07D487/04
- IPC: C07D487/04
![Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use](/abs-image/US/2016/09/06/US09434735B2/abs.jpg.150x150.jpg)
Abstract:
Provided herein is an amorphous form of 4-((4-(Cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-N-methylbenzamide, compositions thereof, and methods of their use for treating or preventing a cancer, in particular solid tumors and hematological cancers as described herein.
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