Invention Grant
US09433700B2 Tissue sealant compositions, vascular closure devices, and uses thereof
有权
组织密封剂组合物，血管闭合装置及其用途
- Patent Title: Tissue sealant compositions, vascular closure devices, and uses thereof
- Patent Title (中): 组织密封剂组合物，血管闭合装置及其用途
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Application No.: US13266161Application Date: 2010-04-27
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Publication No.: US09433700B2Publication Date: 2016-09-06
- Inventor: Bob O. Basore , William L. Neumann , Richard B. Dorshow , Raghavan Rajagopalan
- Applicant: Bob O. Basore , William L. Neumann , Richard B. Dorshow , Raghavan Rajagopalan
- Applicant Address: US MO St. Louis
- Assignee: MediBeacon Inc.
- Current Assignee: MediBeacon Inc.
- Current Assignee Address: US MO St. Louis
- Agent Dennis A. Bennett; Brock Levin
- International Application: PCT/US2010/032519 WO 20100427
- International Announcement: WO2010/129258 WO 20101111
- Main IPC: A61L24/10
- IPC: A61L24/10 ; A61L24/00
Abstract:
The present invention provides tissue sealant compositions and vasculature closure devices useful for the optical detection of tissue seal and/or clot formation. Compositions and devices of the present invention comprise optical dyes which undergo an observable change as the compositions and/or devices are incorporated into a tissue seal and/or clot, for example a change in fluorescence quantum yield and/or a change in visual color including a change in emission and/or absorption wavelength. Tissue sealants and vasculature closure devices of the present invention are useful for visualizing seal and/or clot formation, for example, during or after surgical procedures, after catheter removal, etc. The present invention further provides methods for formation and optical detection of tissue seals or vasculature puncture closures as well as medical kits useful for the formation and optical detection of tissue seals or vasculature puncture closures.
Public/Granted literature
- US20120041479A1 Tissue Sealant Compositions, Vascular Closure Devices, and Uses Thereof Public/Granted day:2012-02-16
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