Invention Grant
US09433699B2 Hydrogel comprising catechol group-coupled chitosan or polyamine and poloxamer comprising thiol group coupled to end thereof, preparation method thereof, and hemostat using same
有权
包含邻苯二酚基团偶联的壳聚糖或多胺和包含与末端偶联的硫醇基的泊洛沙姆的水凝胶,其制备方法和使用其的止血剂
- Patent Title: Hydrogel comprising catechol group-coupled chitosan or polyamine and poloxamer comprising thiol group coupled to end thereof, preparation method thereof, and hemostat using same
- Patent Title (中): 包含邻苯二酚基团偶联的壳聚糖或多胺和包含与末端偶联的硫醇基的泊洛沙姆的水凝胶,其制备方法和使用其的止血剂
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Application No.: US14239538Application Date: 2011-11-21
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Publication No.: US09433699B2Publication Date: 2016-09-06
- Inventor: Haeshin Lee , Moon Sue Lee , Ji Hyun Ryu
- Applicant: Haeshin Lee , Moon Sue Lee , Ji Hyun Ryu
- Applicant Address: KR Seoul
- Assignee: INNOTHERAPY INC.
- Current Assignee: INNOTHERAPY INC.
- Current Assignee Address: KR Seoul
- Agency: Hultquist, PLLC
- Agent Steven J. Hultquist
- Priority: KR10-2011-0121482 20111121
- International Application: PCT/KR2011/008880 WO 20111121
- International Announcement: WO2013/077476 WO 20130530
- Main IPC: A61K8/72
- IPC: A61K8/72 ; A61L24/08 ; A61L24/00 ; A61L24/04 ; A61K51/12 ; A61K9/06

Abstract:
The present invention relates to an adhesive hydrogel composition containing catechol group-coupled chitosan and Pluronic comprising a thiol group coupled to the end thereof, and more specifically, to an adhesive composition which is safe in vivo and in vitro, is temperature sensitive, and has an excellent hemostatic effect and thus can be used as a bioadhesive, and a medical adhesive, an adhesion barrier and a surface adsorption inhibitor comprising the same.
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