In one embodiment, a method of compensating for transmission voltage loss from a switching power supply, can include: (i) receiving a sampling signal that represents an output current of the switching power supply; (ii) delaying the sampling signal to generate a delayed sampling signal; (iii) converting the delayed sampling signal to generate a compensation signal; and (iv) regulating an output voltage of the switching power supply based on the compensation signal to compensate for the transmission voltage loss from the output voltage transmission to a load such that a voltage at the load is maintained as substantially consistent with an expected voltage at the load.