Invention Grant
- Patent Title: Super lewis acidic borate esters as 18F-labeled PET probes
- Patent Title (中): 超级路易斯酸性硼酸酯作为18F标记的PET探针
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Application No.: US14762544Application Date: 2014-01-24
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Publication No.: US09409927B2Publication Date: 2016-08-09
- Inventor: Mark Lee McLaughlin , Haibin Tian
- Applicant: UNIVERSITY OF SOUTH FLORIDA , H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- Applicant Address: US FL Tampa US FL Tampa
- Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.,University of South Florida
- Current Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.,University of South Florida
- Current Assignee Address: US FL Tampa US FL Tampa
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2014/013055 WO 20140124
- International Announcement: WO2014/117028 WO 20140731
- Main IPC: C07F5/04
- IPC: C07F5/04 ; C07B59/00 ; C07K7/56
Abstract:
Compounds having a 1-bora-1-fluoro-2,6,7-trioxabicyclo[2.2.2]octane moiety wherein the fluorine is 18F are described. Also described are reagents for radiolabeling a molecule having Formula I. Method for radiolabeling molecules with the disclosed reagents are also descried, as are radiolabeled molecules prepared thereby.
Public/Granted literature
- US20150361110A1 SUPER LEWIS ACIDIC BORATE ESTERS AS 18F-LABELED PET PROBES Public/Granted day:2015-12-17
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