Methods, systems, and computer-readable media are provided for an application messaging integration framework. An example method includes receiving a user input at a first clinical viewer via an integrated interface. The example method includes sending a message based on the input to a second clinical viewer via an application and messaging integrator. The application and messaging integrator is created to facilitate communication between the first and second clinical viewers. The example method includes updating information at the second clinical viewer based on the message. The example method includes displaying the updated information at the second clinical viewer via the integrated interface.