A centrifugal self-priming mixed and inverted-umbrella shaped aerator is disclosed. A plurality of three-phase mixing tube sets is distributed on a surface of a wheel body (1), each of the three-phase mixing tube sets comprises a plurality of three-phase mixing tubes distributed dispersedly on the surface of the wheel body (1), multiple layers of guide cylinders arranged concentrically extend downward from a bottom of the wheel body (1) with a plurality of vertical siphons distributed on an inner wall of each of the layers of guide cylinders, the number of the siphons distributed in each of the layers of guide cylinders is the same as the number of the three-phase mixing tubes of the corresponding three-phase mixing tube set, each of the three-phase mixing tubes has one end attached to an edge of the wheel body (1) and has the other end communicating with the corresponding siphon, and each of the siphons is provided with a negative-pressure suction tube at a joint with the corresponding three-phase mixing tube.