Invention Grant
US09382553B2 Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound
有权
用于生产1-脱氧纤维素5-磷酸酯（DXP）和/或DXP衍生化合物的宿主细胞和方法
- Patent Title: Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound
- Patent Title (中): 用于生产1-脱氧纤维素5-磷酸酯（DXP）和/或DXP衍生化合物的宿主细胞和方法
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Application No.: US13587826Application Date: 2012-08-16
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Publication No.: US09382553B2Publication Date: 2016-07-05
- Inventor: James Kirby , Jeffrey L. Fortman , Minobu Nishimoto , Jay D. Keasling
- Applicant: James Kirby , Jeffrey L. Fortman , Minobu Nishimoto , Jay D. Keasling
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Lawrence Berkeley National Laboratory
- Agent Robin C. Chiang
- Main IPC: C12N1/21
- IPC: C12N1/21 ; C12N9/04 ; C12P19/02 ; C12P5/00
Abstract:
The present invention provides for a genetically modified host cell capable of producing 1-deoxyxylulose 5-phosphate or 1-deoxy-D-xylulose 5-phosphate (DXP) (12), and optionally one or more DXP derived compounds, comprising: (a) a mutant RibB, or functional variant thereof, capable of catalyzing xylulose 5-phosphate and/or ribulose 5-phosphate to DXP, or (b) a YajO, or functional variant thereof, and a XylB, or functional variant thereof.
Public/Granted literature
- US20130052692A1 Host Cells and Methods for Producing 1-Deoxyxylulose 5-phosphate (DXP) and/or a DXP Derived Compound Public/Granted day:2013-02-28
Information query
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