Invention Grant
- Patent Title: Expression of triple-helical collagen-like products in E. coli
- Patent Title (中): 三螺旋胶原样产物在大肠杆菌中的表达
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Application No.: US13148066Application Date: 2010-02-05
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Publication No.: US09382310B2Publication Date: 2016-07-05
- Inventor: Oleg Mirochnitchenko , Masayori Inouye , Barbara Brodsky , John Ramshaw
- Applicant: Oleg Mirochnitchenko , Masayori Inouye , Barbara Brodsky , John Ramshaw
- Applicant Address: US NJ New Brunswick
- Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- Current Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- Current Assignee Address: US NJ New Brunswick
- Agency: Fox Rothschild LLP
- International Application: PCT/US2010/023318 WO 20100205
- International Announcement: WO2010/091251 WO 20100812
- Main IPC: C07K14/48
- IPC: C07K14/48 ; A61K38/39 ; C07K14/78
Abstract:
Recombinant bacterial triple-helical collagen-like proteins comprising two or more repetitive sequences of Gly-Xaa-Yaa yielding high-stability polymeric constructs without the need for post-translational modifications and which may incorporate one or more functional domains of biological or structural importance. The polymers are capable of high-yield production for a variety of applications.
Public/Granted literature
- US20120116053A1 EXPRESSION OF TRIPLE-HELICAL COLLAGEN-LIKE PRODUCTS IN E.COLI Public/Granted day:2012-05-10
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