Invention Grant
US09382255B2 Substituted pyrrolopyrimidinylamino-benzothiazolones as MKNK kinase inhibitors
有权
取代的吡咯并嘧啶基氨基 - 苯并噻唑酮作为MKNK激酶抑制剂
- Patent Title: Substituted pyrrolopyrimidinylamino-benzothiazolones as MKNK kinase inhibitors
- Patent Title (中): 取代的吡咯并嘧啶基氨基 - 苯并噻唑酮作为MKNK激酶抑制剂
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Application No.: US14429927Application Date: 2013-09-18
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Publication No.: US09382255B2Publication Date: 2016-07-05
- Inventor: Ulrich Klar , Lars Wortmann , Georg Kettschau , Florian Püehler , Philip Lienau , Kirstin Petersen , Andrea Hägebarth , Detlev Sülzle , Anja Richter
- Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
- Applicant Address: DE Berlin
- Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee Address: DE Berlin
- Agency: Resek, Liang & Frank LLP
- Priority: EP12185139 20120920
- International Application: PCT/EP2013/069325 WO 20130918
- International Announcement: WO2014/044691 WO 20140327
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D471/00 ; C07D487/00 ; C07D491/00 ; C07D487/04 ; C07D473/00 ; A61K45/06 ; A61K31/52 ; A61K31/5377 ; C07D473/34

Abstract:
The present invention relates to substituted pyrrolopyrimidinylamino-benzothiazolone compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Public/Granted literature
- US20150239891A1 SUBSTITUTED PYRROLOPYRIMIDINYLAMINO-BENZOTHIAZOLONES AS MKNK KINASE INHIBITORS Public/Granted day:2015-08-27
Information query
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