Invention Grant
US09381209B2 Treatment of squamous cell carcinoma with HSP27 antisense oligonucleotides and radiotherapy
有权
用HSP27反义寡核苷酸和放射治疗鳞状细胞癌
- Patent Title: Treatment of squamous cell carcinoma with HSP27 antisense oligonucleotides and radiotherapy
- Patent Title (中): 用HSP27反义寡核苷酸和放射治疗鳞状细胞癌
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Application No.: US12528118Application Date: 2008-03-04
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Publication No.: US09381209B2Publication Date: 2016-07-05
- Inventor: Claire Rodriguez-Lafrasse , Elie Hadchity
- Applicant: Claire Rodriguez-Lafrasse , Elie Hadchity
- Applicant Address: CA Vancouver
- Assignee: The University of British Columbia
- Current Assignee: The University of British Columbia
- Current Assignee Address: CA Vancouver
- Agency: Larson & Anderson, LLC
- International Application: PCT/CA2008/000419 WO 20080304
- International Announcement: WO2008/106781 WO 20080912
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K31/712 ; A01K67/027 ; A61K31/7088 ; A61K31/7125
Abstract:
Squamous cell carcinomas, such as squamous head and neck cancer, are treated with a combination of radio-therapy and a therapeutic agent that reduces the amount of hsp27 in the squamous cancer cells. In specific embodiments, the therapeutic agent that reduces the amount of hsp27 is an antisense oligonucleotide therapeutic agent.
Public/Granted literature
- US20100324115A1 Treatment of Squamous Cell Carcinoma with HSP27 Antisense Oligonucleotides and Radiotherapy Public/Granted day:2010-12-23
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