Methods, systems, apparatuses, and computer-readable media for utilizing just-in-time polymorphic authentication techniques to secure information are presented. In one or more embodiments, a computing platform may receive, from a computing device, a request to access a user account. In response to receiving the request to access the user account, the computing platform may dynamically select, based on one or more polymorphic authentication factors, an authentication method for authenticating a user of the computing device, and the authentication method may be selected from a plurality of predefined authentication methods. Subsequently, the computing platform may generate one or more authentication prompts based on the selected authentication method. The computing platform then may provide the one or more authentication prompts to the user of the computing device. The authentication prompts that are selected for and presented to a particular user during a given access attempt may vary across different attempts.