Electronic program guide descriptions, of content referenced by the electronic program guide, are user-targeted based on user data. Such user-targeted electronic program guide descriptions aid users in identifying desirable content, thereby increasing user interaction performance with a content presentation device providing such user-targeted electronic program guide descriptions. To generate user-targeted electronic program guide descriptions, received electronic program guide information includes different, alternative or mutually exclusive, content descriptions of a given content item. Such electronic program guide information is compared with the user data and user-targeted content item descriptions is generated from the different content descriptions. A visual electronic program guide, including the user-targeted content item description, is displayed to a user on a physical display device.