Invention Grant
US09274106B2 Methods and devices for detecting binding events via zeta-potential and pharmacologically active compounds and delivery systems identified thereby
有权
用于通过ζ-电位和药理活性化合物检测结合事件的方法和装置以及由此鉴定的递送系统
- Patent Title: Methods and devices for detecting binding events via zeta-potential and pharmacologically active compounds and delivery systems identified thereby
- Patent Title (中): 用于通过ζ-电位和药理活性化合物检测结合事件的方法和装置以及由此鉴定的递送系统
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Application No.: US12593616Application Date: 2008-04-04
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Publication No.: US09274106B2Publication Date: 2016-03-01
- Inventor: Mark Mitchnick , Andrew Loxley , David Fairhurst , Peter Wagner
- Applicant: Mark Mitchnick , Andrew Loxley , David Fairhurst , Peter Wagner
- Applicant Address: US PA Bethlehem
- Assignee: Particle Sciences, Inc.
- Current Assignee: Particle Sciences, Inc.
- Current Assignee Address: US PA Bethlehem
- Agency: Licata & Tyrrell P.C.
- International Application: PCT/US2008/059419 WO 20080404
- International Announcement: WO2009/005868 WO 20090108
- Main IPC: G01N33/542
- IPC: G01N33/542 ; G01N33/543
Abstract:
Methods, devices and arrays for measuring a change in zeta-potential of a surface indicative of a binding event are provided. Pharmacologically active compounds and delivery systems for active pharmaceutical ingredients determined to be pharmacologically active or optimized for pharmacological activity or determined to be useful for delivery of the active pharmaceutical ingredient to a target via measurement of a change in zeta-potential of the compound, ingredient or delivery system are also provided.
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